Pathogen of plants or animals ( including bacterial, toxin), pest, harmful organism and other transgenic organism material, soil and so on. 菌种、毒种、害虫、有害生物体及其它转基因生物材料、土壤等。
These translocation domains exist in bacterial toxin, viral proteins, transcriptional factors, homodomain and synthetic peptides. 这些转运结构域广泛的存在于毒素蛋白、病毒蛋白、转录因子、同源结构域及合成肽当中。
Up to now, some RNA replicon-based preventive and therapeutic vaccines for many disease models ( virus, tumor, bacterial toxin are related) have been researched, and some disadvantages have been improved. 目前已对一些疾病模型基于复制子的治疗性和预防性疫苗进行了研究(涉及的对象包括病毒、肿瘤以及细菌毒素等),并对某些不足之处进行了改进。
Infection experiments ascertained that the bacterial isolates were the cause of the disease, the toxin test showed the bacterium produced endotoxin instead of exotoxin. 人工感染实验均为该病的病原菌,毒素检测试验表明,致病因素主要是内毒素而不是外毒素。
Objective: To construct multivalent vaccine against bacterial diarrhea, which can express coli surface antigen 6 ( CS6) of enterotoxigenic Escherichia coli ( ETEC) and cholera toxin B subunit ( CTB). 目的:构建表达肠毒素性大肠杆菌菌毛抗原基因CS6和霍乱毒素B亚基(CTB)基因的细菌性腹泻基因工程多价疫苗。